Article
Temporal dynamics of norovirus GII.4 variants in Brazil between 2004 and 2012.
PloS one - 1 Jan 2014
Fioretti Julia Monassa, Bello Gonzalo, Rocha Mônica Simões, Victoria Matias, Leite José Paulo Gagliardi, Miagostovich Marize Pereira
Abstract excerpt
Noroviruses (NoVs) are the major cause of acute gastroenteritis outbreaks, and, despite a wide genetic diversity, genotype II.4 is the most prevalent strain worldwide. Mutations and homologous recombination have been proposed as mechanisms driving the epochal evolution of the GII.4, with the emergence of new variants in 1-3-year intervals causing global epidemics. There are no data reporting the dynamics of GII.4...
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