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Article

IL-36γ Augments Host Defense and Immune Responses in Human Female Reproductive Tract Epithelial Cells

17 Jun 2016

Abstract excerpt

IL-36γ is a proinflamatory cytokine which belongs to the IL-1 family of cytokines. It is expressed in the skin and by epithelial cells (ECs) lining lung and gut tissue. We used human 3-D organotypic cells, that recapitulate either in vivo human vaginal or cervical tissue, to explore the possible role of IL-36γ in host defense against pathogens in the human female reproductive tract (FRT). EC were exposed to...

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PMID: 27379082
DOI: 10.3389/fmicb.2016.00955

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