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Article

MTHFR (C677T) CT genotype and CT-apoE3/3 genotypic combination predisposes the risk of ischemic stroke.

Gene - 15 Oct 2016

Vijayan Murali, Chinniah Rathika, Ravi Padma Malini, Sivanadham Ramgopal, Mosses Joseph Arun Kumar, Vellaiappan Neethi Arasu, Krishnan Jeyaram Illiayaraja, Karuppiah Balakrishnan

Abstract excerpt

The predisposition to ischemic stroke (IS) might involve interactions of several genes and environmental factors. The present study was aimed to evaluate the influence of polymorphisms in methylenetetrahydrofolate reductase (MTHFR-C677T) and apolipoprotein-E (apo-E) as risk factors for IS patients in south Indian population. 200 IS patients and 193 age and sex matched controls were genotyped for MTHFR-C677T and...

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PMID: 27378745
DOI: 10.1016/j.gene.2016.06.062

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MTHFR

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