Article
Bioinformatics analysis and genetic diversity of the poliovirus.
Journal of medical microbiology - 1 Dec 2014
Liu Yanhan, Ma Tengfei, Liu Jianzhu, Zhao Xiaona, Cheng Ziqiang, Guo Huijun, Wang Shujing, Xu Ruixue
Abstract excerpt
Poliomyelitis, a disease which can manifest as muscle paralysis, is caused by the poliovirus, which is a human enterovirus and member of the family Picornaviridae that usually transmits by the faecal-oral route. The viruses of the OPV (oral poliovirus attenuated-live vaccine) strains can mutate in the human intestine during replication and some of these mutations can lead to the recovery of serious...
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