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Article

Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes.

Journal of immunology research - 1 Jan 2016

Chimal-Ramírez G Karina, Espinoza-Sánchez Nancy Adriana, Chávez-Sánchez Luis, Arriaga-Pizano Lourdes, Fuentes-Pananá Ezequiel M

Abstract excerpt

Macrophages facilitate breast cancer progression. Macrophages were initially classified as M1 or M2 based on their distinct metabolic programs and then expanded to include antitumoral (M1) and protumoral (M2) activities. However, it is still uncertain what markers define the pro- and antitumoral phenotypes and what conditions lead to their formation. In this study, monocytic cell lines and primary monocytes were...

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Identifiers

PMID: 27376091
DOI: 10.1155/2016/6031486
PMCID: PMC4916292

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CCR7
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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