Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.

doi:10.1038/npp.2016.113

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Article

Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2016

Grünewald Lena, Landaas Elisabeth Toverud, Geissler Julia, Weber Heike, Quast Carina, Röh Simone, Schartner Christoph, Lesch Klaus-Peter, Romanos Marcel, Kittel-Schneider Sarah, Binder Elisabeth, Reif Andreas

Abstract excerpt

The DIRAS2 gene is coding for a small Ras GTPase with so far unknown function. In a previous study, we described the association of DIRAS2 rs1412005, as well as a haplotype containing this polymorphism and located in the promoter region of this gene with attention-deficit/hyperactivity disorder (ADHD). In the present study, we searched for rare variants within or near the DIRAS2 gene that might be associated with...

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PMID: 27364329
DOI: 10.1038/npp.2016.113
PMCID: PMC5101550

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DIRAS2

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