Article
No evidence for association between a functional promoter variant of the Norepinephrine Transporter gene SLC6A2 and ADHD in a family-based sample.
Attention deficit and hyperactivity disorders - 1 Sept 2011
Renner T J, Nguyen T T, Romanos M, Walitza S, Röser C, Reif A, Schäfer H, Warnke A, Gerlach M, Lesch K P
Abstract excerpt
Noradrenergic neurotransmission influences executive functions, attentional performance, and general alertness, involving neuronal networks affected in attention deficit/hyperactivity disorder (ADHD). The norepinephrine transporter facilitates the reuptake of norepinephrine and dopamine in the prefrontal cortex and represents the main target of atomoxetine, an effective drug in the treatment of ADHD. Due to its...
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