Article
PPP2R2C as a candidate gene of a temperament and character trait-based endophenotype of ADHD.
Attention deficit and hyperactivity disorders - 1 Sept 2012
Jacob Christian, Nguyen Thuy Tran, Weißflog Lena, Herrmann Martin, Liedel Stefanie, Zamzow Karin, Jans Thomas, Renner Tobias, Reichert Susanne, Groß-Lesch Silke, Lesch Klaus-Peter, Reif Andreas
Abstract excerpt
There are several lines of evidence that the 4p16 region is a candidate locus of both attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. None of the harbored candidate genes of this region were hitherto shown to be associated with ADHD despite promising functionality. One of the most promising candidate genes in this region is protein phosphatase 2, regulatory subunit B, gamma (PPP2R2C), which,...
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