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Article

Role of common sarcomeric gene polymorphisms in genetic susceptibility to left ventricular dysfunction.

Journal of genetics - 1 Jun 2016

Kumar Surendra, Mishra Avshesh, Srivastava Anshika, Bhatt Mansi, Garg N, Agarwal S K, Pande Shantanu, Mittal Balraj

Abstract excerpt

Mutations in sarcomeric genes are common genetic cause of cardiomyopathies. An intronic 25-bp deletion in cardiac myosin binding protein C (MYBPC3) at 3' region is associated with dilated and hypertrophic cardiomyopathies in Southeast Asia. However, the frequency of sarcomeric gene polymorphisms and associated clinical presentation have not been established with left ventricular dysfunction (LVD). Therefore, the...

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Source

Identifiers

PMID: 27350668
DOI: 10.1007/s12041-016-0623-4

Genes

MYBPC3
CAD
TNNT2
TTN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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