Article
Pharmacogenetics of dipeptidyl peptidase 4 inhibitors in a Taiwanese population with type 2 diabetes.
Oncotarget - 14 Mar 2017
Liao Wen-Ling, Lee Wen-Jane, Chen Ching-Chu, Lu Chieh Hsiang, Chen Chien-Hsiun, Chou Yi-Chun, Lee I-Te, Sheu Wayne H-H, Wu Jer-Yuarn, Yang Chi-Fan, Wang Chung-Hsing, Tsai Fuu-Jen
Abstract excerpt
Dipeptidyl peptidase-4 (DPP-4) inhibitors are oral anti-hyperglycemic drugs enabling effective glycemic control in type 2 diabetes (T2D). Despite DPP-4 inhibitors' advantages, the patients' therapeutic response varies. In this retrospective cohort study, 171 Taiwanese patients with T2D were classified as sensitive or resistant to treatment based on the mean change in HbA1c levels. Using an assumption-free...
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