Article
Better colonisation of newly emerged Bordetella pertussis in the co-infection mouse model study.
Vaccine - 25 Jul 2016
Safarchi Azadeh, Octavia Sophie, Luu Laurence Don Wai, Tay Chin Yen, Sintchenko Vitali, Wood Nicholas, Marshall Helen, McIntyre Peter, Lan Ruiting
Abstract excerpt
Molecular epidemiological data indicates that the resurgence of pertussis (whooping cough) in populations with high vaccine coverage is associated with genomic adaptation of Bordetella pertussis, the causative agent of the disease, to vaccine selection pressure. We have previously shown that in the period after the introduction of acellular pertussis vaccine (ACV), the majority of circulating strains in Australia...
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