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Wharton's jelly mesenchymal stromal cells have contrasting effects on proliferation and phenotype of cancer stem cells from different subtypes of lung cancer.

Experimental cell research - 15 Jul 2016

Vulcano Francesca, Milazzo Luisa, Ciccarelli Carmela, Eramo Adriana, Sette Giovanni, Mauro Annunziata, Macioce Giampiero, Martinelli Andrea, La Torre Renato, Casalbore Patrizia, Hassan Hamisa Jane, Giampaolo Adele

Abstract excerpt

Studies on the role of multipotent mesenchymal stromal cells (MSC) on tumor growth have reported both a tumor promoting and a suppressive effect. The aim of the present study was to determine the effect of MSC isolated from Wharton's jelly of umbilical cord (WJMSC) on lung cancer stem cells (LCSC) derived from human lung tumors: two adenocarcinomas (AC) and two squamous cell carcinomas (SCC). LCSC derived from...

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PMID: 27343631
DOI: 10.1016/j.yexcr.2016.06.003

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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