Article
Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.
Human pathology - 1 Oct 2016
Hackeng Wenzel M, Brosens Lodewijk A A, Poruk Katherine E, Noë Michaël, Hosoda Waki, Poling Justin S, Rizzo Anthony, Campbell-Thompson Martha, Atkinson Mark A, Konukiewitz Björn, Klöppel Günter, Heaphy Christopher M, Meeker Alan K, Wood Laura D
Abstract excerpt
Pancreatic neuroendocrine tumors (PanNETs) are the second most common pancreatic malignancy and cause significant morbidity and mortality. Neuroendocrine microadenomas have been proposed as a potential precursor lesion for sporadic PanNETs. In this study, we applied telomere-specific fluorescent in situ hybridization (FISH) to a series of well-characterized sporadic neuroendocrine microadenomas and investigated...
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