Article
Influenza A Virus-induced expression of ISG20 inhibits viral replication by interacting with nucleoprotein.
Virus genes - 1 Dec 2016
Qu Hongren, Li Jing, Yang Limin, Sun Lei, Liu Wenjun, He Hongxuan
Abstract excerpt
Influenza A virus (IAV) is an important pathogen that has a wide range of hosts and represents a threat to the health of humans and several animal species. IAV infection can induce the transcription of many genes in the host. In the present study, we demonstrated for the first time that three different strains of H1N1 IAV induce the expression of an IFN-stimulated gene, ISG20. We determined the antiviral activity...
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