Article
Effect of Inactivating Mutations on Peptide Conformational Ensembles: The Plant Polypeptide Hormone Systemin.
Journal of chemical information and modeling - 25 Jul 2016
Chowdhury Saikat Dutta, Sarkar Aditya K, Lahiri Ansuman
Abstract excerpt
As part of their basal immune mechanism against insect/herbivore attacks, plants have evolved systemic response mechanisms. Such a systemic wound response in tomato was found to involve an 18 amino acid polypeptide called systemin, the first polypeptide hormone to be discovered in plants. Systematic alanine scanning and deletion studies showed differential modulation in its activity, particularly a major loss of...
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