Article
Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations and ZNF217 amplification in ovarian clear cell carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2014
Huang Hsien-Neng, Lin Ming-Chieh, Huang Wen-Chih, Chiang Ying-Cheng, Kuo Kuan-Ting
Abstract excerpt
AT-rich interactive domain 1A (ARID1A) is a subunit of switch/sucrose non-fermentable (SWI/SNF) complex. Recently, alterations of ARID1A gene, phosphatidylinositol 3-kinase-protein kinase B (PI3K-Akt) pathway and zinc-finger protein 217 (ZNF217) gene have been identified as frequent molecular genetic changes in ovarian clear cell carcinoma. The relationships between these events have not been studied and...
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