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Article

Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy

26 Nov 2015

Abstract excerpt

INTRODUCTION: Cardiac involvement is a common feature in muscular dystrophies. It presents as heart failure and/or arrhythmia. Traditionally, dystrophic cardiomyopathy is treated with symptom-relieving medications. Identification of disease-causing genes and investigation on pathogenic mechanisms have opened new opportunities to treat dystrophic cardiomyopathy with gene therapy. Replacing/repairing the mutated...

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PMID: 27340611
DOI: 10.1517/21678707.2016.1124039

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