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Multiplex reverse transcriptase–polymerase chain reaction screening in childhood acute myeloblastic leukemia

1 Feb 2001

Abstract excerpt

To determine the incidence of leukemia-specific rearrangements, 60 cases of childhood acute myeloblastic leukemia and transient myeloproliferative disorder were screened with a novel multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) assay, and the results were correlated with the cytogenetic findings. The RT-PCR assay detects 28 different fusion genes and more than 80 different fusion transcript...

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Share to Acute Lymphoblastic Leukemia research
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PMID: 11157501
DOI: 10.1182/blood.v97.3.805

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