Article
Polymorphism in the chemokine receptor 7 gene (CCR7) is associated with previous myocardial infarction in patients undergoing elective coronary angiography.
International journal of immunogenetics - 1 Aug 2016
Wołkow P P, Drabik L, Totoń-Żurańska J, Kuś K, Foryś J, Słowik A, Pera J, Godlewski J, Tomala M, Żmudka K, Olszanecki R, Jawień J, Korbut R
Abstract excerpt
Coronary artery disease (CAD) remains a major cause of death in developed countries. Both environmental and, less known, genetic factors contribute to progression of CAD to myocardial infarction (MI). Immune system is activated in patients with CAD through dendritic cells (DCs), which present plaque antigens to T lymphocytes. Production of proinflammatory cytokines by activated T cells contributes to plaque...
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