Article
Association Between Tissue Inhibitor of Metalloproteinase-3 Gene Methylation and Gastric Cancer Risk: A Meta-Analysis.
Genetic testing and molecular biomarkers - 1 Aug 2016
Cao Jinghua, Li Zhenfeng, Yang Lijuan, Liu Chengxia, Luan Xiying
Abstract excerpt
BACKGROUND: The tumor suppressor gene tissue inhibitor of metalloproteinase-3 (TIMP-3) has been reported to be frequently and significantly downregulated in gastric cancer, and its downregulation is correlated with hypermethylation in its promoter region. However, the association between TIMP-3 methylation and gastric cancer risk remains unclear. AIM: In this study, we assessed the relationship between TIMP-3...
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