Article
Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer.
PloS one - 1 Jan 2016
Veluchamy John Pradeep, Spanholtz Jan, Tordoir Marleen, Thijssen Victor L, Heideman Daniëlle A M, Verheul Henk M W, de Gruijl Tanja D, van der Vliet Hans J
Abstract excerpt
The ability of Natural Killer (NK) cells to kill tumor targets has been extensively studied in various hematological malignancies. However, NK cell therapy directed against solid tumors is still in early development. Epidermal Growth Factor Receptor (EGFR) targeted therapies using monoclonal antibodies (mAbs) such as cetuximab and panitumumab are widely used for the treatment of metastatic colorectal cancer...
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