Article
Family-based association study between autism and glutamate receptor 6 gene in Chinese Han trios.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Nov 2004
Shuang Mei, Liu Jing, Jia Mei Xiang, Yang Jian Zhong, Wu Su Ping, Gong Xiao Hong, Ling Yan Su, Ruan Yan, Yang Xiao Ling, Zhang Dai
Abstract excerpt
The glutamate pathways are involved in diverse processes such as learning and memory, epilepsy, and they play important roles in neural plasticity, neural development, and neurodegeneration. It has been proposed that autism could be a hypoglutamatergic disorder. Recently, Jamain et al. reported that the glutamate receptor 6 (GluR6 or GRIK2) is in linkage disequilibrium with autism. In the present study, the...
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