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Article

Depletion of BBS Protein LZTFL1 Affects Growth and Causes Retinal Degeneration in Mice.

Journal of genetics and genomics = Yi chuan xue bao - 20 Jun 2016

Jiang Jiangsong, Promchan Kanyarat, Jiang Hong, Awasthi Parirokh, Marshall Heather, Harned Adam, Natarajan Ven

Abstract excerpt

Bardet-Biedl syndrome (BBS) is a heterogeneous disease characterized by deficiencies in various organs that are caused by defects in genes involved in the genesis, structural maintenance, and protein trafficking of cilia. Leucine zipper transcription factor-like 1 (LZTFL1) has been identified as a BBS protein (BBS17), because patients with mutations in this gene exhibit the common BBS phenotypes. In this study,...

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Source

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Identifiers

PMID: 27312011
DOI: 10.1016/j.jgg.2015.11.006
PMCID: PMC4925197

Genes

LZTFL1
BBS9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Depletion of BBS Protein LZTFL1 Affects Growth and Causes Retinal Degeneration in Mice.PMID 27312011Read ↗

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