Article
Serum Amyloid A Type 1 Gene Polymorphism in Egyptian Children with Familial Mediterranean Fever.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2016
Wilson Manal, Abou-Elalla Amany A, Zakaria Mervat Talaat, Marzouk Huda, Fayed Hala Lotfy, Hanna Mariam Onsy F
Abstract excerpt
BACKGROUND: Since spontaneous inflammation is an important contributor to familial Mediterranean fever (FMF), genetic variants mediating inflammation are of interest. We investigated gene variants in the acute-phase serum amyloid A type 1 (SAA1), a sensitive marker of inflammatory activity, and their association with susceptibility and severity of FMF. METHODS: The genotypes of 2 single-nucleotide polymorphisms...
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