Article
Analysis of the modifying effects of SAA1, SAA2 and TNF-alpha gene polymorphisms on development of amyloidosis in FMF patients.
The Turkish journal of pediatrics - 1 Jan 2000
Yilmaz Engin, Balci Banu, Kutlay Sim, Ozen Seza, Ertürk Sensuvar, Oner Ayse, Beşbaş Nesrin, Bakkaloğlu Ayşin
Abstract excerpt
The aim of this study was to examine whether polymorphisms at serum amyloid A (SAA) and tumor necrosis factor-alpha (TNF-alpha) genes are associated with development of amyloidosis in familial Mediterranean fever (FMF) patients. Seventy-three FMF patients with amyloidosis and 100 other FMF patients without amyloidosis of known genotypes and 100 healthy control subjects were analyzed. There was a significant...
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