Article
Rad51C-ATXN7 fusion gene expression in colorectal tumors.
Molecular cancer - 13 Jun 2016
Kalvala Arjun, Gao Li, Aguila Brittany, Dotts Kathleen, Rahman Mohammad, Nana-Sinkam Serge P, Zhou Xiaoping, Wang Qi-En, Amann Joseph, Otterson Gregory A, Villalona-Calero Miguel A, Duan Wenrui
Abstract excerpt
BACKGROUND: Fusion proteins have unique oncogenic properties and their identification can be useful either as diagnostic or therapeutic targets. Next generation sequencing data have previously shown a fusion gene formed between Rad51C and ATXN7 genes in the MCF7 breast cancer cell line. However, the existence of this fusion gene in colorectal patient tumor tissues is largely still unknown. METHODS: We evaluated...
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