Article
Helicobacter pylori cagA status, vacA genotypes and ulcer disease.
European journal of gastroenterology & hepatology - 1 May 1998
Stephens J C, Stewart J A, Folwell A M, Rathbone B J
Abstract excerpt
OBJECTIVE: Helicobacter pylori is the causative organism of peptic ulcer disease and has two putative virulence determinants: the cagA gene which encodes a protein of unknown function in 60% of strains, and the vacA gene, which is present in all strains, although active cytotoxin is produced in only about 50% of these. The relationship between genotypes of both cagA and vacA and resultant gastroduodenal pathology...
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