Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells.

Oncotarget - 5 Jul 2016

Guimarães Douglas M, Almeida Luciana O, Martins Manoela D, Warner Kristy A, Silva Alan R S, Vargas Pablo A, Nunes Fabio D, Squarize Cristiane H, Nör Jacques E, Castilho Rogerio M

Abstract excerpt

Mucoepidermoid carcinoma (MEC) is the most common malignancy of salivary glands. The response of MEC to chemotherapy is unpredictable, and recent advances in cancer biology suggest the involvement of cancer stem cells (CSCs) in tumor progression and chemoresistance and radioresistance phenotype. We found that histone acetyltransferase inhibitors (HDACi) were capable of disrupting CSCs in MEC. Furthermore,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Cisplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Deacetylase Inhibitors

Share to Inhibitory Concentration 50

Share to Neoplasm Transplantation

Share to Salivary Gland Neoplasms

Share to Salivary Glands

Share to Tissue Array Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 27285758
DOI: 10.18632/oncotarget.9884
PMCID: PMC5173147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells.PMID 27285758Read ↗

Targeting cancer stem cells in squamous cell carcinomaSemantic proximity Read ↗

Targeting Cancer Stem Cell Markers or Pathways: A Potential Therapeutic Strategy for Oral Cancer TreatmentSemantic proximity Read ↗

Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinomaSemantic proximity Read ↗

Targeting Notch and EGFR signaling in human mucoepidermoid carcinomaSemantic proximity Read ↗

Cancer stem cells in head and neck squamous cell cancer.Semantic proximity Read ↗

Invasive oral cancer stem cells display resistance to ionising radiationSemantic proximity Read ↗

Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression.Semantic proximity Read ↗

Alteration of cancer stem cell-like phenotype by histone deacetylase inhibitors in squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

A subpopulation of CD133+ cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapySemantic proximity Read ↗

Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.Semantic proximity Read ↗

Mitochondrial Stress–Mediated Targeting of Quiescent Cancer Stem Cells in Oral Squamous Cell CarcinomaSemantic proximity Read ↗

Cancer Stem Cell Epigenetics And ChemoresistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.