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Article

RBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma

10 Jun 2016

Abstract excerpt

Renal cell carcinoma (RCC), one of the most common kidney cancers, has a poor prognosis. Epithelial to mesenchymal transition (EMT) is a hallmark of carcinoma invasion and metastasis. Several studies have examined the molecular regulation of EMT, but the relationship between histone demethylases and EMT is little understood. In this study, we investigated the role of retinoblastoma-binding protein-2 (RBP2), a...

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Share to Epigenetics and DNA Methylation
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PMID: 27282106
DOI: 10.1038/emm.2016.37

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