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Epithelial-mesenchymal transition associated markers in sarcomatoid transformation of clear cell renal cell carcinoma

13 Jun 2024

Abstract excerpt

Epithelial-mesenchymal transition (EMT) plays a pivotal role in the development and progression of many cancers. Partial EMT (pEMT) could represent a critical step in tumor migration and dissemination. Sarcomatoid renal cell carcinoma (sRCC) is an aggressive form of renal cell carcinoma (RCC) composed of a carcinomatous (sRCC-Ca) and sarcomatous (sRCC-Sa) component. The role of (p)EMT in the progression of RCC to...

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PMID: 38876079
DOI: 10.1016/j.yexmp.2024.104909

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