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Emerging role of F-box proteins in the regulation of epithelial-mesenchymal transition and stem cells in human cancers

18 Apr 2019

Abstract excerpt

Emerging evidence shows that epithelial-mesenchymal transition (EMT) plays a crucial role in tumor invasion, metastasis, cancer stem cells, and drug resistance. Data obtained thus far have revealed that F-box proteins are critically involved in the regulation of the EMT process and stem cell differentiation in human cancers. In this review, we will briefly describe the role of EMT and stem cells in cell...

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PMID: 30999935
DOI: 10.1186/s13287-019-1222-0

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