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Article

Association of interleukin-6 promoter polymorphism with rheumatoid arthritis: a meta-analysis with trial sequential analysis.

Clinical rheumatology - 1 Feb 2022

Shao Ming, Xie Huimin, Yang Hui, Xu Wei, Chen Yuting, Gao Xing, Guan Shiyang, Xu Shengqian, Shuai Zongwen, Pan Faming

Abstract excerpt

OBJECTIVES: The association of interleukin-6 (IL-6) -174G/C (rs1800795) and IL-6 -572G/C (rs1800796) single-nucleotide polymorphism (SNP) with the risk of acquiring rheumatoid arthritis (RA) was inconsistent among previous studies. This paper aims to investigate the association between IL-6 promoter polymorphism with RA in different ethnics. METHODS: Relevant studies were searched using Medline and Google Search...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Reproducibility of Results
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Share to Genetic Predisposition to Disease
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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34494214
DOI: 10.1007/s10067-021-05886-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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