Article
Relapsed diffuse large B-cell lymphoma present different genomic profiles between early and late relapses.
Oncotarget - 20 Dec 2016
Broséus Julien, Chen Gaili, Hergalant Sébastien, Ramstein Gérard, Mounier Nicolas, Guéant Jean-Louis, Feugier Pierre, Gisselbrecht Christian, Thieblemont Catherine, Houlgatte Rémi
Abstract excerpt
Despite major advances in first-line treatment, a significant proportion of patients with diffuse large B-cell lymphoma (DLBCL) will experience treatment failure. Prognosis is particularly poor for relapses occurring less than one year after the end of first-line treatment (early relapses/ER) compared to those occurring more than one year after (late relapses/LR). To better understand genomic alterations...
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