Article
Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients.
Oxidative medicine and cellular longevity - 1 Jan 2016
Jiménez-Osorio Angélica Saraí, González-Reyes Susana, García-Niño Wylly Ramsés, Moreno-Macías Hortensia, Rodríguez-Arellano Martha Eunice, Vargas-Alarcón Gilberto, Zúñiga Joaquín, Barquera Rodrigo, Pedraza-Chaverri José
Abstract excerpt
The nuclear factor-erythroid 2- (NF-E2-) related factor 2 (Nrf2) is abated and its ability to reduce oxidative stress is impaired in type 2 diabetes and obesity. Thus, the aim of this study was to explore if polymorphisms in Nrf2 and target genes are associated with diabetes and obesity in Mexican mestizo subjects. The rs1800566 of NAD(P)H: quinone oxidoreductase 1 (NQO1) gene, rs7211 of thioredoxin interacting...
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