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Nuclear and mitochondrial DNA in blastocoele fluid and embryo culture medium: evidence and potential clinical use

6 Jun 2016

Abstract excerpt

The ability to screen embryos for aneuploidy or inherited disorders in a minimally invasive manner may represent a major advancement for the future of embryo viability assessment. Recent studies have demonstrated that both blastocoele fluid and embryo culture medium contain genetic material, which can be isolated and subjected to downstream genetic analysis. The blastocoele fluid may represent an alternative...

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PMID: 27270971
DOI: 10.1093/humrep/dew132

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