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Article

Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study

25 Aug 2017

Abstract excerpt

STUDY QUESTION: Can quantification of mitochondrial DNA (mtDNA) in trophectoderm (TE) biopsy samples provide information concerning the viability of a blastocyst, potentially enhancing embryo selection and improving IVF treatment outcomes? SUMMARY ANSWER: This study demonstrated that euploid blastocysts of good morphology, but with high mtDNA levels had a greatly reduced implantation potential. WHAT IS KNOWN...

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Share to Mitochondrial Function and Pathology
Share to Prenatal Screening and Diagnostics
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29040520
DOI: 10.1093/humrep/dex292

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