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Article

Early predictors of behavioural problems in pre-schoolers - a longitudinal study of constitutional and environmental main and interaction effects.

BMC pediatrics - 7 Jun 2016

Agnafors Sara, Sydsjö Gunilla, Comasco Erika, Bladh Marie, Oreland Lars, Svedin Carl Göran

Abstract excerpt

BACKGROUND: The early environment is important for child development and wellbeing. Gene-by-environment studies investigating the impact of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and the Brain Derived Neurotrophic Factor (BDNF) Val66Met polymorphisms by life events on mental health and behaviour problems have been inconclusive. Methodological differences regarding sample sizes, study...

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Identifiers

PMID: 27267363
DOI: 10.1186/s12887-016-0614-x
PMCID: PMC4895962

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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