Article
5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study.
Journal of child psychology and psychiatry, and allied disciplines - 1 Jul 2010
Kumsta Robert, Stevens Suzanne, Brookes Keeley, Schlotz Wolff, Castle Jenny, Beckett Celia, Kreppner Jana, Rutter Michael, Sonuga-Barke Edmund
Abstract excerpt
BACKGROUND: A common polymorphism in the serotonin transporter gene (SLC6A4, 5HTT) has been repeatedly shown to moderate the influence of childhood adversity and stressful life events on the development of psychopathology. Using data from the English and Romanian Adoptee Study, a prospective-longitudinal study of individuals (n = 125) exposed to severe early institutional deprivation (ID), we tested whether the...
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