Article
Triazolopyrimidines as a New Herbicidal Lead for Combating Weed Resistance Associated with Acetohydroxyacid Synthase Mutation.
Journal of agricultural and food chemistry - 22 Jun 2016
Liu Yu-Chao, Qu Ren-Yu, Chen Qiong, Yang Jing-Fang, Cong-Wei Niu, Zhen Xi, Yang Guang-Fu
Abstract excerpt
Acetohydroxyacid synthase (AHAS; also known as acetolactate synthase; EC 2.2.1.6, formerly EC 4.1.3.18) is the first common enzyme in the biosynthetic pathway leading to the branched-chain amino acids in plants and a wide range of microorganisms. Weed resistance to AHAS-inhibiting herbicides, increasing at an exponential rate, is becoming a global problem and leading to an urgent demand of developing novel...
Topics
- Acetolactate Synthase
- Arabidopsis
- Brassicaceae
- Enzyme Inhibitors
- Herbicide Resistance
- Herbicides
- Kinetics
- Models, Molecular
- Mutation
- Plant Proteins
- Plant Weeds