Article
[Association of polymorphisms of miRNA biogenesis related genes DICER and DROSHA with azoospermia].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2016
Fu Mei, Xu Kehui, Ye Junjie, Xu Wenming
Abstract excerpt
OBJECTIVE: To assess the association of polymorphisms of miRNA biogenesis related genes DICER and DROSHA with azoospermia. METHODS: For 330 patients with primary azoospermia and 282 fertile male controls, single nucleotide polymorphisms (SNPs) of DICER rs3742330 and DROSHA rs10719 were determined with a restriction fragment length polymorphism (RFLP) method. RESULTS: For the SNP rs3742330, the frequency of A...
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