Article
Immunomodulatory Device Promotes a Shift of Circulating Monocytes to a Less Inflammatory Phenotype in Chronic Hemodialysis Patients.
ASAIO journal (American Society for Artificial Internal Organs : 1992) - 1 Jan 2000
Szamosfalvi Balazs, Westover Angela, Buffington Deborah, Yevzlin Alexander, Humes H David
Abstract excerpt
Patients with end-stage renal disease (ESRD) on chronic hemodialysis (HD) suffer accelerated morbidity and mortality rates caused by cardiovascular disease and infections. Chronic inflammation plays a critical role in these poor outcomes. The activated monocyte (MO) has become a prime therapeutic target to modulate this inflammatory process. A selective cytopheretic device (SCD) was evaluated to assess its...
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