Article
Fate mapping of Trps1 daughter cells during cardiac development using novel Trps1-Cre mice.
Genesis (New York, N.Y. : 2000) - 1 Jul 2016
Nomir Ahmed G, Takeuchi Yuto, Fujikawa Junji, El Sharaby Ashraf A, Wakisaka Satoshi, Abe Makoto
Abstract excerpt
Tricho-rhino-phalangeal syndrome (TRPS) is a rare congenital disorder that is characterized by abnormal hair growth and skeletal deformities. These result in sparse hair, short stature, and early onset of joint problems. Recent reports have shown that a relatively high proportion of patients with TRPS exhibit a broad range of congenital heart defects. To determine the regulation of Trps1 transcription in vivo, we...
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