Article
The Unique Characteristics of MET Exon 14 Mutation in Chinese Patients with NSCLC.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2016
Liu Si-Yang, Gou Lan-Ying, Li An-Na, Lou Na-Na, Gao Hong-Fei, Su Jian, Yang Jin-Ji, Zhang Xu-Chao, Shao Yang, Dong Zhong-Yi, Zhou Qing, Zhong Wen-Zhao, Wu Yi-Long
Abstract excerpt
INTRODUCTION: Predictive biomarkers of mesenchymal-to-epithelial transition factor (MET)-targeted therapy remain elusive. Since the discovery of the MNNG HOS Transforming gene (MET) exon 14 mutation, it has been found to have the best potential to become one precise biomarker for MET-targeted therapy. Here, we present the unique characteristics of MET exon 14 mutations in Chinese patients with NSCLC. METHODS: A...
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