Article
MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer.
Oncotarget - 5 Jul 2016
Zheng Difan, Wang Rui, Ye Ting, Yu Su, Hu Haichuan, Shen Xuxia, Li Yuan, Ji Hongbin, Sun Yihua, Chen Haiquan
Abstract excerpt
PURPOSE: Recurrent MET exon 14 splicing has been revealed in lung cancers and is a promising therapeutic target. Because we have limited knowledge about the natural history of MET mutant tumors, the current study was aiming to determine the clinical and pathological characteristics in non-small cell lung cancers (NSCLC). RESULTS: Twenty-three patients (1.3%) were positive for MET exon 14 skipping. Patients with...
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