Article
Genomewide copy number analysis of Müllerian adenosarcoma identified chromosomal instability in the aggressive subgroup.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2016
Lee Jen-Chieh, Lu Tzu-Pin, Changou Chun A, Liang Cher-Wei, Huang Hsien-Neng, Lauria Alexandra, Huang Hsuan-Ying, Lin Chin-Yao, Chiang Ying-Cheng, Davidson Ben, Lin Ming-Chieh, Kuo Kuan-Ting
Abstract excerpt
Müllerian adenosarcomas are malignant gynecologic neoplasms. Advanced staging and sarcomatous overgrowth predict poor prognosis. Because the genomic landscape remains poorly understood, we conducted this study to characterize the genomewide copy number variations in adenosarcomas. Sixteen tumors, including eight with and eight without sarcomatous overgrowth, were subjected to a molecular inversion probe array...
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