The Added Value of Family Material in the Discovery of Multiple Sclerosis Genes.

doi:10.1016/j.neuron.2016.05.027

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Article

The Added Value of Family Material in the Discovery of Multiple Sclerosis Genes.

Neuron - 1 Jun 2016

Hain Heather S, Hakonarson Hakon

Abstract excerpt

A mutation in a nuclear receptor (NR1H3) gene was detected in a familial, progressive form of multiple sclerosis (PPMS). Further analyses showed a significant association between a common NR1H3 variant in PPMS patients and loss of function for the encoded protein.

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PMID: 27253441
DOI: 10.1016/j.neuron.2016.05.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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