Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KIR2DL2 and KIR2DS2 as genetic markers to the methotrexate response in rheumatoid arthritis patients.

Immunopharmacology and immunotoxicology - 1 Aug 2016

Velarde-de la Cruz Erandi Enif, Sánchez-Hernández Pedro Ernesto, Muñoz-Valle José Francisco, Palafox-Sánchez Claudia Azucena, Ramírez-de Los Santos Saúl, Graciano-Machuca Omar, García-Iglesias Trinidad, Montoya-Buelna Margarita, Ramírez-Dueñas María Guadalupe

Abstract excerpt

CONTEXT: Disease Modifying Anti-Rheumatic Drugs (DMARDs) are aimed to interfere with rheumatoid arthritis (RA) progression and reduce the joint damage; however, not all patients respond alike. Killer-cell immunoglobulin-like receptors (KIR) and their ligands, human leucocyte antigen class I (HLA-I), have been associated with RA pathology; therefore, KIR and HLA genes may influence the treatment response....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Methotrexate

Share to Receptors, KIR

Share to Receptors, KIR2DL2

Source

Identifiers

PMID: 27251940
DOI: 10.1080/08923973.2016.1194429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KIR2DL2 and KIR2DS2 as genetic markers to the methotrexate response in rheumatoid arthritis patients.PMID 27251940Read ↗

Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment.Semantic proximity Read ↗

Associations of killer cell immunoglobulin- like receptor genes with rheumatoid arthritis.Semantic proximity Read ↗

Killer immunoglobulin-like receptor and human leukocyte antigen-C genotypes in rheumatoid arthritis primary responders and non-responders to anti-TNF-α therapy.Semantic proximity Read ↗

Association between KIR gene polymorphisms and rheumatoid arthritis susceptibility: A meta-analysis.Semantic proximity Read ↗

Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid ArthritisSemantic proximity Read ↗

Associations of killer cell immunoglobulin like receptors with rheumatoid arthritis among North Indian population.Semantic proximity Read ↗

Killer cell immunoglobulin-like receptor gene's repertoire in rheumatoid arthritis.Semantic proximity Read ↗

Association of Killer Cell Immunoglobulin- Like Receptor Genes in Iranian Patients with Rheumatoid Arthritis.Semantic proximity Read ↗

Influence of CD94 and NKG2A variants on susceptibility to rheumatoid arthritis and efficacy of anti-TNF treatment.Semantic proximity Read ↗

Polymorphisms Involved in Response to Biological Agents Used in Rheumatoid Arthritis.Semantic proximity Read ↗

Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis.Semantic proximity Read ↗

KIRs and their HLA ligands in remitting-relapsing multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.