Article
Association of Killer Cell Immunoglobulin- Like Receptor Genes in Iranian Patients with Rheumatoid Arthritis.
PloS one - 1 Jan 2015
Nazari Masoumeh, Mahmoudi Mahdi, Rahmani Farzaneh, Akhlaghi Masoomeh, Beigy Maani, Azarian Maryam, Shamsian Elmira, Akhtari Maryam, Mansouri Reza
Abstract excerpt
OBJECTIVES: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by persistent synovitis, ultimately leading to cartilage and bone degeneration. Natural Killer cells and CD28 null T-cells are suspected as role players in RA pathogenesis. These cells are similar in feature and function, as they both exert their cytotoxic effect via Killer Cell Immunoglobulin- Like Receptors (KIR) on their...
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