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Article

Killer immunoglobulin-like receptor and human leukocyte antigen-C genotypes in rheumatoid arthritis primary responders and non-responders to anti-TNF-α therapy.

Rheumatology international - 1 Jun 2012

McGeough Cathy M, Berrar Daniel, Wright Gary, Mathews Clare, Gilmore Paula, Cunningham Rodat T, Bjourson Anthony J

Abstract excerpt

The identification of patients who will respond to anti-tumor necrosis factor alpha (anti-TNF-α) therapy will improve the efficacy, safety, and economic impact of these agents. We investigated whether killer cell immunoglobulin-like receptor (KIR) genes are related to response to anti-TNF-α therapy in patients with rheumatoid arthritis (RA). Sixty-four RA patients and 100 healthy controls were genotyped for 16...

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Source

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Identifiers

PMID: 21373785
DOI: 10.1007/s00296-011-1838-6
PMCID: PMC3364412

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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