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Article

Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function.

American journal of physiology. Cell physiology - 1 Jul 2016

Najmi Mitra, Zhao Rongbao, Fiser Andras, Goldman I David

Abstract excerpt

The proton-coupled folate transporter (PCFT) mediates folate absorption across the brush-border membrane of the proximal small intestine and is required for folate transport across the choroid plexus into the cerebrospinal fluid. In this study, the functional role and accessibility of the seven PCFT Trp residues were assessed by the substituted-cysteine accessibility method. Six Trp residues at a lipid-aqueous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27251438
DOI: 10.1152/ajpcell.00084.2016
PMCID: PMC4967132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function.PMID 27251438Read ↗

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